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The way it would work would probably be (although this is just conjecture) a certain energy frequency that destroys the parts of the brain that allow one to be sentient enough for the flood. in what form of energy this frequency would be, it is not known, it would have to be a Incredibly high frequ...

If the Forerunner was a groop of people then shouldnt we be calling them Forerunners. Or could it be just one all Knowing almightey person that usses machines to do there biding. That would explane the huge amount of A.I.s hanging around.